NeuroLens

High-resolution brain PET for research. Stand-alone, or inside your MRI from 1.5T to 7T.

Rendering · system in development
Investigational device · Not CE marked · Research use only

1 mm

1 mm³ effective resolution. Design target

PET + MRI

simultaneously, in your 1.5T to 7T scanner

2× sensitivity

versus standard PET. Whole brain and cerebellum in one field of view. Design target

Resolution

Resolution matters.

Try it yourself: slide along the line.

Resolution simulation based on data from BrainWeb anatomy.

1.0 mm

NeuroLens · design target

Resolution (FWHM)

~4 mm: typical whole-body PET
1.6 mm: today’s best dedicated brain PET
1 mm: NeuroLens, design target

Your setup

Works with your imaging systems.

In your MRI

1.5T to 7T. Slides into the bore like a head coil.

Next to your PET/CT

Combined with the CT or MR images you already acquire.

Stand-alone

A dedicated brain PET on its own table. No MRI needed.

Rendering · system in development · RF coil design by TeslaDC.

Open research platform. Reconstruction and analysis software included, plus full list-mode and detector raw data access to every event for your own methods.

Our track record · BrainPET 7T

Our detectors, proven at 7T.

The BrainPET 7T is a research prototype of Forschungszentrum Jülich, built on our detectors and readout electronics [1]. It shows what our technology already does inside a 7T MRI.

Anthropomorphic head phantom imaged with the BrainPET 7T: PET, fused PET/MR and MR in three axial slices — Anthropomorphic head phantom, simultaneous PET and MR (MPRAGE) at 7T, 33 MBq ¹⁸F, 20 min. Rows: PET, fusion, MR (MR brightened for display). Image: C. Lerche, INM-4, Forschungszentrum Jülich [3].

7 T

Simultaneous PET and MR inside a 7T scanner. Negligible effect on B₀ and B1 homogeneity [2]

25 cm

Long axial field of view: the whole brain in one position [3]

57 kcps/MBq

Very high sensitivity, about 3× the previous BrainPET 3T [3]

327 kcps

Peak NECR at 16.6 kBq/mL, for high count rates [4]

Today · prototype, measured

BrainPET 7T

1.6 mm

spatial resolution, about 4 mm³ volumetric

3-layer depth of interaction [5]

Next · NeuroLens

1 mm

1 mm³ effective resolution

Design target. New detector with continuous depth of interaction.

BrainPET 7T is a research prototype of Forschungszentrum Jülich (INM-4), built on Hyperion detector and readout technology. The values in this section were measured with it; values for NeuroLens are design targets.

The NeuroLens project · Horizon Europe

Next: clinical trial.

NeuroLens Horizon Europe project

Eight partners build the first NeuroLens system and evaluate it clinically, starting 2027.

Selected for funding. Grant agreement in preparation.

250 Trial participants

Planned at LMU Munich and Hospital Clínic Barcelona.

NeuroLens for your research

Let's connect.

We are building systems for research sites now. Leave your details and we will get back to you within a week.

Prefer email? neurolens@hyperion-his.com

References

B. Weissler et al., Hyperion III, a flexible PET detector platform for simultaneous PET/MRI. IEEE NSS/MIC 2019.
C. Lerche et al., MR compatibility evaluation of a BrainPET insert for UHF-MR systems and neuroscientific applications. IEEE NSS/MIC/RTSD 2024.
C. Lerche et al., Imaging performance of a human 7T BrainPET insert. ISMRM 2026, Cape Town.
D. Niekämper et al., Investigation of the timing calibration and coincidence time resolution of a BrainPET-7T insert with staggered-layer scintillation detectors. IEEE Trans. Radiat. Plasma Med. Sci., 2026, doi:10.1109/TRPMS.2026.3700015.
C. Lerche et al., Fast maximum likelihood positioning for a staggered layer scintillation PET detector. Phys. Med. Biol. 70 (2025) 175018, doi:10.1088/1361-6560/adf8ab.

Images and data courtesy of Dr. Christoph Lerche, Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich. Press release: Brain imaging on a new level, Forschungszentrum Jülich, April 2025.

Our detector platform and earlier projects: hyperion-his.com